Coronavirus disease 2019 (COVID-19) Situation Report-73 available at Ģ. European Centre for Disease Prevention and Control. Key words: COVID-19, DM, Kariadi Hospitalġ. Almost all patients suffered from disseminated intravascular coagulation (DIC) and severe acute inflammation. Mortality and morbidity of patients with COVID-19 and DM was very high. There was no significant difference between the life and death groups. Coagulation (D-dimer, fibrinogen) and acute inflammatory (CRP, procalsitonin) markers were increased, respectively 3937.4 ng/mL 496.1 mg/dL 16.6 mg/L 12 ng/mL. Average of glycemic control (HbA1c 9.7%) and O 2 saturation (Sat O2 90%) were poor.
Percentage of death was 42.9% (18 out of 42). Nearly half of the cases needed intensive care (40.5%) at arrival. The majority of patients denied contact or travel history (>75%). Cough, fever, and shortness of breath were the most prevalent chief complaints. Most cases were >50 years of age (64.3%). The number of patients with COVID-19 and DM was 42 out of 436 cases (9.63%). Data analysis was performed with SPSS v.24 (IBM, New York, USA). death) and different tests was performed. Laboratory result: RBG, HbA1c, creatinine, O 2 saturation, C-reactive protein (CRP), proclasitonin, D-dimers, and fibrinogen were grouped according to patient output (life vs. Baseline characteristics: age, sex, chief complaints, contact and travel history, type and place of care, duration of treatment, comorbidity, and diabetes treatment options. Diagnosis of COVID-19 infection: positive PCR from nasopharyngeal-oropharyngeal smear. Diagnosis of DM: history of diabetes and/or RBG >200 mg/dL or HbA1c >7%. The characteristics and outcomes of patients with COVID-19 and DM in the RSDK have not been reported yet.ĭata were taken from the RSDK medical record. Diabetes mellitus (DM) known to decreases the immune system and worsens the inflammatory reaction. Kariadi General Hospital (RSDK) is one of the referral hospital with 436 confirmed cases of COVID-19 until July 10 th 2020. Hampir seluruh pasien mengalami gangguan koagulasi dan inflamasi akut.Ĭentral Java province has the 4 th largest cases of COVID-19 in Indonesia with more than 8.000 cases. Mortalitas dan morbiditas COVID-19 sangat tinggi pada DM. Tidak ada beda bermakna antara kelompok hidup dan mati. Rerata penanda gangguan koagulasi (D-dimer, fibrinogen) dan inflamasi akut (CRP, prokalsitonin) meningkat, berturut-turut 3937,4 ng/mL 496,1 mg/dL 16,6 mg/L 12 ng/mL. Rerata kendali glikemik (HbA1c 9,7%) dan saturasi O 2 (Sat O 2 90%) buruk. Hampir separuh perlu perawatan intensif sejak awal (40,5%). Mayoritas pasien menyangkal riwayat kontak ataupun bepergian (>75%). Batuk, demam, dan sesak nafas adalah keluhan tersering. Pasien COVID-19 dengan DM periode Maret-10 Juli 2020 sebanyak 42 dari total 436 kasus (9,63%). Analisis dengan SPSS v.24 (IBM, New York, USA). Pemeriksaan penunjang: GDS, HbA1c, kreatinin, saturasi O 2, C-reactive protein (CRP), proklasitonin, D-dimer, dan fibrinogen dikelompokkan berdasarkan keluaran (hidup vs. Karakteristik dasar: usia, jenis kelamin, keluhan, riwayat kontak, riwayat perjalanan, jenis dan tempat perawatan, lama perawatan, komorbid, serta terapi DM.
Diagnosis COVID-19: PCR usapan nasofaring-orofaring positif. Diagnosis DM: riwayat DM dan/atau GDS >200 mg/dL atau HbA1c >7%. Karakteristik dan keluaran pasien COVID-19 dengan DM di RSDK belum pernah dilaporkan sebelumnya.ĭata dari rekam medis RSDK.
Diabetes mellitus (DM) diketahui menurunkan sistem imun dan memperburuk reaksi inflamasi.
Kariadi (RSDK) sebagai RS rujukan memiliki 436 kasus terkonfirmasi COVID-19 per 10 Juli 2020. Jawa Tengah merupakan propinsi dengan kasus COVID-19 terbanyak ke-4 di Indonesia (lebih dari 8.000 kasus).